Light-Stress Response Mediated by the Transcription Factor KlMga2 in the Yeast Kluyveromyces lactis

In unicellular organisms like yeasts, which do not have specialized tissues for protection against environmental challenges, the presence of cellular mechanisms to respond and adapt stress conditions is fundamental. this work, we aimed investigate response light in Kluyveromyces lactis . Yeast lacks light-sensing proteins; however, Saccharomyces cerevisiae has been reported by increasing hydrogen peroxide level triggering nuclear translocation Msn2. This a stress-sensitive transcription factor also present K. To yeast, analyzed different phenotypes generated deletion hypoxia responsive lipid biosynthesis Kl Mga2. Alterations growth rate, mitochondrial functioning, ROS metabolism, fatty acid provide evidence that was source Mga2 had role light-stress response. The involvement Msn2 Crz1 explored, but latter showed no function